Lomex Soft Capsule (Anti Diarrhea)

Lomex Soft Capsule (Anti Diarrhea)

In traditional medicine, Summer Savory is mentioned as an anti-Diarrhea and antispasmodic herb. The terpenes and terpenoids present in essential oil of Summer Savory have antispasmodic and antimicrobial properties, therefore it can also be used in the case of microbial Diarrheas.

In  a clinical trial, 56 patients with type I Diarrhea, took Lumex soft capsule or placebo for 3 days, one soft capsule every 8 hours. The degree of recovery in the first 24 hours in the Lumex soft capsule group was 63% and in the placebo group 25.9%. Also the prevalence of cramps 24 hours after the beginning of treatment was 35.7% in the Lumex soft capsule group and 68% in the placebo group.

Detailed Specifications
Adjuvant treatment for non-infectious diarrhea (reduction in cramps, number of trips to the toilet and duration of the diarrhea)
30 Soft capsule - 50 mg
summer savory Essential oil
1 soft capsule every 8 hours, for 3 days
carvacrol, p-cymene
Based on presence of 22.5-17.5 mg carvacrol per soft capsule. 
1- Medical literature and articles
Diarrheal diseases are still one of the main causes of debilitation and death throughout the world. The first measure for treatment of diarrhea is to supply water and electrolytes and other measures serve to alleviate symptoms such as nausea, vomiting and cramps and to shorten the course of the disease. By surveying the biological functions of phytoconstituents extracted from plants with antispasmodic mechanisms, delay in intestinal transit, inhibition of intestinal motility, stimulation of water absorption or reduction of electrolyte secretion, the use of antidiarrheal medicinal plants has approved by some studies.(1) The terpenes and terpenoids present in essential oil of summer savory have antispasmodic and antimicrobial properties, therefore it can also be used in the case of microbial diarrheas. 
2- Pharmacological Studies
In comparison of the antispasmodic properties of essential oil of summer savory with that of atropine and dicyclomine against spasms induced by KCl and acetyl choline in isolated rat ileum, it was demonstrated that summer savory essential oil has relaxant properties of the ileum smooth muscles. Also, summer savory essential oil inhibits diarrhea induced by caster oil in mice.
3- Clinical Trials
In a controlled, double-blind clinical trial, 71 patients with type I diarrhea in the range of 10-65 years of age were randomly divided into two groups of Lumex Oral Drop (39 patients) or placebo (32 patients) and were monitored over a period of 3 days. The administered dose was 20 drops three times a day and patients were followed up after 24, 48 and 72 hours after the initial visit. The data was statistically analyzed using SPSS. Based on the results of this study, the mean time needed for the diarrhea to stop was 17.3 hours for the group receiving Lumex Oral Drop and was significant in comparison to the group receiving placebo (35.3 hours) (p=0.013). After 48 hours, the number of times of diarrhea was lower in the group receiving Lumex Oral Drop, which was statistically significant in comparison to the placebo group (p=0.003). Also, 24 hours after the beginning of treatment, the prevalence of cramps was 15.4% in those taking Lumex Oral Drop and 40.6% in the placebo group (p=0.16). The results of this study manifested the value of Lumex Oral Drop for alleviation of symptoms of diarrhea in relation to the placebo.(2) With regard to the studies carried out, Lumex Oral Drop can be used as a fast acting antidiarrheal adjuvant treatment with no adverse effects. 
In another controlled, randomized, double-blind clinical trial, 56 patients with type I diarrhea aging 10-65 were randomly divided into two groups: Lumex Soft Capsule (29 patients) or placebo (27 patients), to take for 3 days, one soft capsule every 8 hours. The patients were re-evaluated 24, 48 and 72 hours after the beginning of the study and the gathered data was analyzed using statistical t-test and Mann-Whitney test. Based on the results of this study, the degree of recovery in the first 24 hours in the Lumex Soft Capsule group was 63% and in the placebo group 25.9% and this difference was observed as statistically significant (p=0.013). This difference was also significant 48 and 72 hours after the beginning of the disease as well (p<0.001 and p=0.058, respectively). The prevalence of cramps 24 hours after the beginning of treatment was 35.7% in the Lumex Soft Capsule group and 68% in the placebo group (p=0.058). Regarding the prevalence of cramps, 48 hours after the first visit, significant difference existed between the group receiving Lumex Soft Capsule and the placebo group (p<0.0001), and was significantly less in the Lumex Soft Capsule group. The mean time for the diarrhea to stop was 25.7±22.6 hours in the Lumex Soft Capsule group and 50.2±25.7 in the placebo group and this difference was observed as statistically significant (p=0.001). The time for the cramps to stop was 24±21.5 hours in the placebo group and 10.8±13 hours in the Lumex Soft Capsule group (p=0.038). The results of this study demonstrated the value of the herbal medicine Lumex Soft Capsule for alleviation of the symptoms of diarrhea in comparison with the placebo.
Pregnancy and lactation. 
Regarding its safety, the FDA places summer savory in the GRAS (Generally Regarded As Safe) category and its use with the recommended doses is safe. Also, with the recommended dosage for the recommended duration, no adverse reaction has been reported. 
No reported drug interaction
  •  During the course of treatment, it is essential to take sufficient fluids including ORS (Oral Rehydration Solution). 
  • In case the diarrhea persists after 3 days of treatment, an in cases of presence of fever or blood in stool, consult your physician.
  • Keep the medicine away from sight and reach of children, in closed container, away from light and in 15-30°C.
  • Keep this leaflet; you may need to read it again.
  • ISO 17025
  • CANADA GMP
  • IR GMP
  • ISO 9001
  • I.R.I.FDO
  • ISO 10004
  • ISO 10668

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  • Product Code: SOJ030
  • Availability: In Stock
  • 3.46 €

Tags: Non-Infectious Diarrhea Treatment Soft Capsule/Non-Infectious Diarrhea Treatment/Soft Capsule