Fennelin Soft Capsule (Menstruation Pain Reliever)

Fennelin Soft Capsule (Menstruation Pain Reliever)

Fennel has been used for a long time in Iranian traditional medicines for increasing lactation, carminative and etc. Also, Fennel contains phytoestrogens (substances similar to female hormone) that reduces the discomfort of bleeding and Menstrual cramps. 

To compare the effect of this product with Mephnaminic Acid, a sample of 30 women aged 15 to 24 who were suffering from primary Dysmenorrhea, were studied In 3 periods of Menstruation. Results showed that both products alleviated the pain quite effectively, so researchers concluded that Fennel can be used as a safe and effective herbal medicine for early painful Menstruation.

Detailed Specifications
  • Increase milk flow in nursing mother
  • Primary dysmenorrhea
30 Soft Capsule - 30 mg
Essential oil of Foeniculum vulgare
One capsule each 4 hours
Trans-anthol, Methyl chavicol, fenechon ,stragol.
Based on 21-27 mg anethole in each soft capsule.
Dysmenorrhea is a very common condition in women. More than 50 percent of women experience some pain during menstruation. In about 10% of women menstrual pain is of such intensity that makes one to three days of total rest imperative.
This condition can adversely affect a woman's social interactions, can hinder her from attending school and can cause massive economic loss by taking out a large number of working hours.
Dysmenorrhea is of either primary or secondary type; no diagnosable pelvic condition exists in the former type.
Foeniculum vulgare has been used for a very long time in Iranian transitional medical practice. It has been used for increasing lactation, increasing urine, as carminative and for discharging stones formed in urinary passages.
To study pharmacological effects of Foeniculum Vulgare on isolated uteral cramps and to calculate LD50 value in rats, Exitosine (0.1, 1, 10 mg/ml) and (5*10 -5 M) E2 prostaglandin were used to induce muscular cramps in rats. Different doses of Foeniculum Vulgare reduced the intensity of cramps induced by the two above named drugs (25, 50 mg/ml for Exitosine and 10, 25 mg/ml for E2 prostaglandin respectively). Essential oil of Foeniculum Vulgare did reduce the frequency of E2 prostoglandin induced cramps, but it did not reduce the frequency of cramps induced by Exitosine. LD 50 calculated using the moving average method was 1326 mg/kg. The following is a summary of a few clinical tests performed with the aim of measuring the effect of Foeniculum  Vulgare in alleviating primary dysmenorrhea
1-      To compare the effect of Foeniculum Vulgare with that of Mephnaminic Acid ,a sample of 30 women aged 15 to 24 who were suffering from moderate to intense primary dysmenorrhea were studied over 3 menstruations  .The first menstrual period was taken with no drugs (control period ). Mephnaminic Acid was administered during the second menstrual period with a dosage of 250mg each 6 hours. For the third menstrual period, essential oil of foeniculum vulgare was administered with a dosage of 25 drop of 2% solution of foeniculum Vulgare each 4 hours. Results show that both drugs alleviated the pain quite effectively (p<0.001) ,with average time to manifestation of the effect being 67.5+_ 48.9 minutes for Mephnaminic Acid and 75+_ 48.9 for foeniculum vulgare. The difference here was not statistically significant (P= 0.57). During 2ed and 3rd days of menstruation, mephnaminic Acid proved, on average ,more effective (p<0.05); but there was not much difference between the two drugs during the rest of menstrual period .NO side effects were reported for Mephnaminic Acid. It was thus shown that Foeniculum Vulgare based drug is a safe and effective way of combating primary dysmenorrhea.
2-      A double-blind placebo-controlled test was performed on a sample of 60 unmarried female students who were living in the dormitory of Tehran university .Subjects were aged 17 to 25 and all suffered from primary dysmenorrhea with an intensity of 2 to 3 in Andersch and Milsom subjective scale, with pain present in all or most periods of menstruation. After preliminary examination and confirmation of primary dysmenorrheal, subjects were randomly grouped in six groups, naming of groups being in accordance with all possible permutations of the three letters A, B and C .Each subject was put under study for three consecutive menstrual periods. Subjects were given 1% or 2% essential oil of foeniculum Vulgare and were asked to have forty drops right at the beginning of menstrual pain. They were allowed to use the same dosage at 4 hour intervals if necessary .In case the pain continued unabated for 2 hours after the intake, the subject was allowed to use her usual painkiller (she was asked to record this in a special form) .Results are indicative of a statistically meaningful difference between those treated with 1% or 2% essential oil of Foeniculum Vulgare and those who were given placebo (p<0.05) .Researchers came to the conclusion that 1% and 2% essential oils of foeniculum vulgare drastically reduce menstrual pain in 52.8% and 67.2% of subjects and caused ""some alleviation"" in 47.2% and 28.6% of subjects respectively. These results are comparable to those obtained for Non-Steroid Anti-Inflammatory Drugs or NSAIDs.
3-      To compare the effect of essential oil of foeniculum vulgare with that of ibuprofen, a test was conducted on 120 high school girls who suffered from moderate to intense primary dysmenorrhea. These had been randomly collected from 4 high schools in the city of Mashhad. For the menstrual cycle immediately before the test cycles (this we will call the control cycle), subjects were asked to fill up a form (form No.1) which measured the intensity of dysmenorrhea using multi-dimensional oral presentation grading criteria. Half of subjects were given ibuprofen and the other half were given foeniculum vulgare essential oil (400mg ibuprofen each 4-8 hours and 20 to 30 drops of the essential oil each 4-8 hours as needed) during their next menstrual cycle. In the third menstrual cycle, the ibuprofen group and the foeniculum Vulgare group were reverse and the test repeated. Subjects filled another form (form No.2) in each cycle after the control cycle. According to the results obtained from the analysis of data collected from 100 participants, 2 % essential oil of foeniculum vulgare reduced both the intensity (p<0.001) and the duration (p=0.000) of dysmenorrhea. The reduction, however, was not significantly different from that achieved by Ibuprofen .The need for taking additional sedatives was also similar in the two groups (p=0.148). While 2% essential oil of foeniculum vulgare reduced the average time of bleeding (p=0.045), the volume of blood was not affected in a meaningful way. While the essential oil of foeniculum vulgare did not affect the amount of blood, Ibuprofen did (p=0.038) .subjects were equally satisfied with essential oil of foeniculum vulgare and with ibuprofen (p=NS) .Researchers came to the conclusion that for those who are better disposed toward alternative medicine, or for those who adversely react to NSAIDs, 2% essential oil of foeniculum vulgare can be the medication of choice and a good replacement for ibuprofen, even though the exact mechanism of its effect remains obscure.
4-      In a prospective clinical test, 60 school girls suffering from pre-menstrual syndrome or PMS were studied during 5 consecutive menstrual cycles, the first cycle passing with no drugs and as control cycle, foeniculum vulgare used during the second and third cycle and chamomile used during the fourth and fifth cycle. Subjects were asked to fill questionnaires on 16 signs of PMS and dysmenorrhea. According to the results of this study, only three signs or symptoms were significantly better reduced by taking chamomile or foeniculum vulgare based drugs than by taking placebo. These symptoms were ache in abdomen and pelvis, weakness and tiredness, and anger and depression (p<0.05).
There were differences for other symptoms too but these were not statistically significant. Researchers came to the conclusion that chamomile and foeniculum vulgare based drugs are effective only in alleviating the above said three symptoms of dysmenorrhea/PMS, with chamomile based drugs being more effective in reducing anger and depression as well as pain in pelvis and abdomen, and foeniculum vulgare based drugs being more effective in combating tiredness and weakness.
Foeniculum vulgare has also been used against amenorrhea and for improving lactation.
  • Those with a record of allergy to foeniculum vulgare or its extracts should refrain from taking the drug
  • Not suitable for pregnant women
  • those afflicted with allergic asthma
  • seizure
  • diseases of liver and cancers
  • Not suitable for children
Increase in menstrual blood
Trans-anthol induces the cytochrome p450 enzyme system. This substance has estrogenic effects and is metabolized in liver. Its metabolites are discharged through urine.
  • like other drugs, keep out of the reach children
  • to achieve the best results; begin use with the start of menstruation
  • this drug can increase the volume of menstrual blood; it is normal but stop usage and consult your physician in case of exorbitant bleeding.
  • Keep away from light and in 15 to 30 degrees Celsius.
  • ISO 17025
  • CANADA GMP
  • IR GMP
  • ISO 9001
  • I.R.I.FDO
  • ISO 10004
  • ISO 10668

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  • Product Code: SPJ031
  • Availability: In Stock
  • 3.49 €

Tags: Primary Dysmenorrhea Treatment & Milk Increaser Soft Capsule/Primary Dysmenorrhea Treatment/Milk Increaser/Soft Capsule